첨부문서 : Pre IR_YS Ju.pdf
[Project Leader : Young Seok Ju Organization : KAIST GSMSE]
Genome sequencing, bioinformatic analysis, and validation using organoid models
(e.g., Discovery of new target, Mode of Action, New drug candidate, Drug delivery…)
We whole-genome sequence human tumor and paired normal tissues. Using well-developed bioinformatic analysis pipelines and professional skills, we detect accurate somatic mutations, ranging from point mutations to structural variations, from the cancer genome sequences. Some variants of interests are further validated using in-house organoid models.
Mutations in cancers can be used for prediction of optimal anti-cancer drugs for ptients.
Stage of Research
(e.g., Discovery, validation, scale-up for production…)
Discovery (70%), scale-up for production (30%)